Kinome Profiling Reveals Abnormal Activity of Kinases in Skeletal Muscle From Adults With Obesity and Insulin Resistance

CONTEXT: Obesity-related insulin resistance (OIR) is one of the main contributors to type 2 diabetes and other metabolic diseases. Protein kinases are implicated in insulin signaling and glucose metabolism. Molecular mechanisms underlying OIR involving global kinase activities remain incompletely un...

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Veröffentlicht in:J Clin Endocrinol Metab
Hauptverfasser: Qi, Yue, Zhang, Xiangmin, Seyoum, Berhane, Msallaty, Zaher, Mallisho, Abdullah, Caruso, Michael, Damacharla, Divyasri, Ma, Danjun, Al-janabi, Wissam, Tagett, Rebecca, Alharbi, Majed, Calme, Griffin, Mestareehi, Aktham, Draghici, Sorin, Abou-Samra, Abdul, Kowluru, Anjaneyulu, Yi, Zhengping
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Clinical Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991621/
https://ncbi.nlm.nih.gov/pubmed/31652310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgz115
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