Acyclovir for Mechanically Ventilated Patients With Herpes Simplex Virus Oropharyngeal Reactivation: A Randomized Clinical Trial

IMPORTANCE: The role of herpes simplex virus (HSV) reactivation on morbidity and mortality in patients in the intensive care unit requiring mechanical ventilation remains unknown. OBJECTIVE: To determine whether preemptive treatment with intravenous acyclovir reduces the duration of mechanical venti...

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Detalhes bibliográficos
Publicado no:JAMA Intern Med
Main Authors: Luyt, Charles-Edouard, Forel, Jean-Marie, Hajage, David, Jaber, Samir, Cayot-Constantin, Sophie, Rimmelé, Thomas, Coupez, Elisabeth, Lu, Qin, Diallo, Mamadou Hassimiou, Penot-Ragon, Christine, Clavel, Marc, Schwebel, Carole, Timsit, Jean-François, Bedos, Jean-Pierre, Hauw-Berlemont, Caroline, Bourenne, Jérémy, Mayaux, Julien, Lefrant, Jean-Yves, Mira, Jean-Paul, Combes, Alain, Wolff, Michel, Chastre, Jean, Papazian, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990840/
https://ncbi.nlm.nih.gov/pubmed/31841577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamainternmed.2019.5713
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