Effect of Dasatinib vs Imatinib in the Treatment of Pediatric Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Randomized Clinical Trial

IMPORTANCE: A randomized clinical trial is needed to determine whether the second-generation Abl–tyrosine kinase inhibitor dasatinib is more effective than the first-generation inhibitor imatinib mesylate for childhood Philadelphia chromosome–positive acute lymphoblastic leukemia (ALL). OBJECTIVE: T...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Shen, Shuhong, Chen, Xiaojuan, Cai, Jiaoyang, Yu, Jie, Gao, Ju, Hu, Shaoyan, Zhai, Xiaowen, Liang, Changda, Ju, Xiuli, Jiang, Hua, Jin, Runming, Wu, Xuedong, Wang, Ningling, Tian, Xin, Pan, Kaili, Jiang, Hui, Sun, Lirong, Fang, Yongjun, Li, Chi-kong, Hu, Qun, Yang, Minghua, Zhu, Yiping, Zhang, Hui, Li, Chunfu, Pei, Deqing, Jeha, Sima, Yang, Jun J, Cheng, Cheng, Tang, Jingyan, Zhu, Xiaofan, Pui, Ching-Hon
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2020
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990720/
https://ncbi.nlm.nih.gov/pubmed/31944221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2019.5868
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