Association of Apolipoprotein E ε4 With Medial Temporal Tau Independent of Amyloid-β

IMPORTANCE: Apolipoprotein E ε4 (APOEε4) is the single most important genetic risk factor for Alzheimer disease. While APOEε4 is associated with increased amyloid-β burden, its association with cerebral tau pathology has been controversial. OBJECTIVE: To determine whether APOEε4 is associated with m...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Therriault, Joseph, Benedet, Andrea L., Pascoal, Tharick A., Mathotaarachchi, Sulantha, Chamoun, Mira, Savard, Melissa, Thomas, Emilie, Kang, Min Su, Lussier, Firoza, Tissot, Cecile, Parsons, Marlee, Qureshi, Muhammad Naveed Iqbal, Vitali, Paolo, Massarweh, Gassan, Soucy, Jean-Paul, Rej, Soham, Saha-Chaudhuri, Paramita, Gauthier, Serge, Rosa-Neto, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2020
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990684/
https://ncbi.nlm.nih.gov/pubmed/31860000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2019.4421
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