Association of Apolipoprotein E ε4 With Medial Temporal Tau Independent of Amyloid-β

IMPORTANCE: Apolipoprotein E ε4 (APOEε4) is the single most important genetic risk factor for Alzheimer disease. While APOEε4 is associated with increased amyloid-β burden, its association with cerebral tau pathology has been controversial. OBJECTIVE: To determine whether APOEε4 is associated with m...

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Publicat a:JAMA Neurol
Autors principals: Therriault, Joseph, Benedet, Andrea L., Pascoal, Tharick A., Mathotaarachchi, Sulantha, Chamoun, Mira, Savard, Melissa, Thomas, Emilie, Kang, Min Su, Lussier, Firoza, Tissot, Cecile, Parsons, Marlee, Qureshi, Muhammad Naveed Iqbal, Vitali, Paolo, Massarweh, Gassan, Soucy, Jean-Paul, Rej, Soham, Saha-Chaudhuri, Paramita, Gauthier, Serge, Rosa-Neto, Pedro
Format: Artigo
Idioma:Inglês
Publicat: American Medical Association 2020
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990684/
https://ncbi.nlm.nih.gov/pubmed/31860000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2019.4421
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