Association of Apolipoprotein E ε4 With Medial Temporal Tau Independent of Amyloid-β

IMPORTANCE: Apolipoprotein E ε4 (APOEε4) is the single most important genetic risk factor for Alzheimer disease. While APOEε4 is associated with increased amyloid-β burden, its association with cerebral tau pathology has been controversial. OBJECTIVE: To determine whether APOEε4 is associated with m...

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Gepubliceerd in:JAMA Neurol
Hoofdauteurs: Therriault, Joseph, Benedet, Andrea L., Pascoal, Tharick A., Mathotaarachchi, Sulantha, Chamoun, Mira, Savard, Melissa, Thomas, Emilie, Kang, Min Su, Lussier, Firoza, Tissot, Cecile, Parsons, Marlee, Qureshi, Muhammad Naveed Iqbal, Vitali, Paolo, Massarweh, Gassan, Soucy, Jean-Paul, Rej, Soham, Saha-Chaudhuri, Paramita, Gauthier, Serge, Rosa-Neto, Pedro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Medical Association 2020
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Original Investigation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990684/
https://ncbi.nlm.nih.gov/pubmed/31860000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2019.4421
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