The heterogeneous clinical and pathological landscapes of metastatic Braf-mutated colorectal cancer

Colorectal cancer (CRC) is a complex and molecularly heterogeneous disease representing one of the most frequent causes of cancer-related death worldwide. About 8–15% of CRCs harbor a mutation in BRAF gene, a proto-oncogene involved in cell proliferation, differentiation and survival through the MAP...

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Vydáno v:Cancer Cell Int
Hlavní autoři: Fanelli, Giuseppe Nicolò, Dal Pozzo, Carlo Alberto, Depetris, Ilaria, Schirripa, Marta, Brignola, Stefano, Biason, Paola, Balistreri, Mariangela, Dal Santo, Luca, Lonardi, Sara, Munari, Giada, Loupakis, Fotios, Fassan, Matteo
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990491/
https://ncbi.nlm.nih.gov/pubmed/32015690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-020-1117-2
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