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Required G(K1) to Suppress Automaticity of iPSC-CMs Depends Strongly on I(K1) Model Structure

Human-induced pluripotent stem cells derived cardiomyocytes (hiPSC-CMs) are a virtually endless source of human cardiomyocytes that may become a great tool for safety pharmacology; however, their electrical phenotype is immature: they show spontaneous action potentials (APs) and an unstable and depo...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Fabbri, Alan, Goversen, Birgit, Vos, Marc A., van Veen, Toon A.B., de Boer, Teun P.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990378/
https://ncbi.nlm.nih.gov/pubmed/31623886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.08.040
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