CD163(ΔSRCR5) MARC-145 Cells Resist PRRSV-2 Infection via Inhibiting Virus Uncoating, Which Requires the Interaction of CD163 With Calpain 1

Porcine alveolar macrophages without the CD163 SRCR5 domain are resistant to porcine reproductive and respiratory syndrome virus (PRRSV) infection. However, whether the deletion of CD163 SRCR5 in MARC-145 cells confers resistance to PRRSV and interaction of which of the host proteins with CD163 is i...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Yu, Piao, Wei, Ruiping, Dong, Wenjuan, Zhu, Zhenbang, Zhang, Xiaoxiao, Chen, Yaosheng, Liu, Xiaohong, Guo, Chunhe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990145/
https://ncbi.nlm.nih.gov/pubmed/32038556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.03115
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