Characterization of LAG-3, CTLA-4, and CD8(+) TIL density and their joint influence on the prognosis of patients with esophageal squamous cell carcinoma

BACKGROUND: We aimed to characterize the relationships of lymphocyte activation gene-3 (LAG-3) expression, cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) expression, and CD8(+) tumor-infiltrating lymphocyte (TIL) density, and to investigate the joint prognostic impact of these three markers in...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Wang, Wenjia, Chen, Donglai, Zhao, Yuhuan, Zhao, Ting, Wen, Junmiao, Mao, Yiming, Chen, Chang, Sang, Yonghua, Zhang, Yongsheng, Chen, Yongbing
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990025/
https://ncbi.nlm.nih.gov/pubmed/32042792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.11.38
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