Integrated metabolomics and lipidomics profiling of hippocampus reveal metabolite biomarkers in a rat model of chronic unpredictable mild stress-induced depression

BACKGROUND: Prolonged exposure to stress triggers depression, threatening human health. Thus, to thoroughly understand the underlying pathophysiologic mechanism of chronic unpredictable mild stress (CUMS)-induced depression is urgently needed. Ultra-high-performance liquid chromatography-mass spectr...

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Udgivet i:Ann Transl Med
Main Authors: Geng, Chunmei, Qiao, Yi, Guo, Yujin, Han, Wenxiu, Wu, Bin, Wang, Changshui, Zhang, Jun, Chen, Dan, Yang, Mengqi, Jiang, Pei
Format: Artigo
Sprog:Inglês
Udgivet: AME Publishing Company 2019
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990017/
https://ncbi.nlm.nih.gov/pubmed/32042797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.11.21
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