Arctigenin inhibits prostate tumor growth in high-fat diet fed mice through dual actions on adipose tissue and tumor

This study investigated the inhibitory effect of arctigenin, a novel anti-inflammatory lignan, on prostate cancer in obese conditions both in vitro and in vivo. In vitro obese models were established by co-culture of mouse adipocytes 3T3-L1 with androgen-sensitive LNCaP human prostate cancer cells,...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Hao, Qiongyu, Diaz, Tanya, Verduzco, Alejandro del Rio, Magyar, Clara E., Zhong, Jin, Elshimali, Yahya, Rettig, Matthew B., Henning, Susanne M., Vadgama, Jaydutt V., Wang, Piwen
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989655/
https://ncbi.nlm.nih.gov/pubmed/31996731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58354-3
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