OSU-6162, a Sigma1R Ligand in Low Doses, Can Further Increase the Effects of Cocaine Self-Administration on Accumbal D2R Heteroreceptor Complexes

Cocaine was previously shown to act at the Sigma1R which is a target for counteracting cocaine actions. It therefore becomes of interest to test if the monoamine stabilizer (–) OSU-6162 (OSU-6162) with a nanomolar affinity for the Sigma1R can acutely modulate in low doses the effects of cocaine self...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurotox Res
Prif Awduron: Borroto-Escuela, Dasiel O., Romero-Fernandez, Wilber, Wydra, Karolina, Zhou, Zilong, Suder, Agata, Filip, Malgorzata, Fuxe, Kjell
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer US 2019
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989596/
https://ncbi.nlm.nih.gov/pubmed/31782100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-019-00134-7
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