A Novel Loss-of-Function Variant in the Chloride Ion Channel Gene Clcn2 Associates with Atrial Fibrillation

Atrial Fibrillation (AF) is the most common cardiac arrhythmia. Its pathogenesis is complex and poorly understood. Whole exome sequencing of Danish families with AF revealed a novel four nucleotide deletion c.1041_1044del in CLCN2 shared by affected individuals. We aimed to investigate the role of g...

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Publicado no:Sci Rep
Main Authors: Hansen, Thea Hyttel, Yan, Yannan, Ahlberg, Gustav, Vad, Oliver Bundgaard, Refsgaard, Lena, dos Santos, Joana Larupa, Mutsaers, Nancy, Svendsen, Jesper Hastrup, Olesen, Morten Salling, Bentzen, Bo Hjorth, Schmitt, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989500/
https://ncbi.nlm.nih.gov/pubmed/31996765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58475-9
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