Tissue pO(2) distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy

Hypoxia in solid tumors is thought to be an important factor in resistance to therapy, but the extreme microscopic heterogeneity of the partial pressures of oxygen (pO(2)) between the capillaries makes it difficult to characterize the scope of this phenomenon without invasive sampling of oxygen dist...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Cao, Xu, Rao Allu, Srinivasa, Jiang, Shudong, Jia, Mengyu, Gunn, Jason R., Yao, Cuiping, LaRochelle, Ethan P., Shell, Jennifer R., Bruza, Petr, Gladstone, David J., Jarvis, Lesley A., Tian, Jie, Vinogradov, Sergei A., Pogue, Brian W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989492/
https://ncbi.nlm.nih.gov/pubmed/31996677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14415-9
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