Tissue pO(2) distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy

Hypoxia in solid tumors is thought to be an important factor in resistance to therapy, but the extreme microscopic heterogeneity of the partial pressures of oxygen (pO(2)) between the capillaries makes it difficult to characterize the scope of this phenomenon without invasive sampling of oxygen dist...

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Foilsithe in:Nat Commun
Main Authors: Cao, Xu, Rao Allu, Srinivasa, Jiang, Shudong, Jia, Mengyu, Gunn, Jason R., Yao, Cuiping, LaRochelle, Ethan P., Shell, Jennifer R., Bruza, Petr, Gladstone, David J., Jarvis, Lesley A., Tian, Jie, Vinogradov, Sergei A., Pogue, Brian W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989492/
https://ncbi.nlm.nih.gov/pubmed/31996677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14415-9
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