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Mitoepigenetics and Its Emerging Roles in Cancer

In human beings, there is a ∼16,569 bp circular mitochondrial DNA (mtDNA) encoding 22 tRNAs, 12S and 16S rRNAs, 13 polypeptides that constitute the central core of ETC/OxPhos complexes, and some non-coding RNAs. Recently, mtDNA has been shown to have some covalent modifications such as methylation o...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Dong, Zhen, Pu, Longjun, Cui, Hongjuan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989428/
https://ncbi.nlm.nih.gov/pubmed/32039210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00004
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