Effect of plasma membrane monoamine transporter genetic variants on pharmacokinetics of metformin in humans

Metformin, an oral hypoglycemic agent belonging to biguanide class, is widely used to treat type 2 diabetes mellitus, and several drug transporters such as organic cation transporters (OCTs), multidrug and toxin extrusion transporter (MATE), and plasma membrane monoamine transporter (PMAT) are thoug...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Transl Clin Pharmacol
Prif Awduron: Moon, Seol Ju, Oh, Jaeseong, Lee, Seung Hwan, Choi, Yewon, Yu, Kyung-Sang, Chung, Jae-Yong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Korean Society for Clinical Pharmacology and Therapeutics 2018
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989255/
https://ncbi.nlm.nih.gov/pubmed/32055553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2018.26.2.79
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