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Antiepileptic drug-induced severe cutaneous adverse reactions and HLA alleles: A report of five cases with lymphocyte activation test

Antiepileptic drugs (AEDs) can induce severe cutaneous adverse reactions (SCARs) such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. We performed HLA genotyping and lymphocyte activation tests (LATs) fo...

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Détails bibliographiques
Publié dans:Transl Clin Pharmacol
Auteurs principaux: Kim, Eun-Young, Kim, Mi-Yeong, Park, Chan Sun, Choi, Jae-Hyeog, Ghim, Jong-Lyul, Kim, Ho-Sook, Shin, Jae-Gook
Format: Artigo
Langue:Inglês
Publié: Korean Society for Clinical Pharmacology and Therapeutics 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989248/
https://ncbi.nlm.nih.gov/pubmed/32055583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2019.27.2.64
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