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Comparison of various estimation methods for the parameters of Michaelis-Menten equation based on in vitro elimination kinetic simulation data
The Michaelis-Menten equation is one of the best-known models describing the enzyme kinetics of in vitro drug elimination experiments, and takes a form of equation relating reaction rate (V) to the substrate concentration ([S]) via the maximum reaction rate (V(max)) and the Michaelis constant (K(m))...
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| Udgivet i: | Transl Clin Pharmacol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Korean Society for Clinical Pharmacology and Therapeutics
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6989224/ https://ncbi.nlm.nih.gov/pubmed/32055546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12793/tcp.2018.26.1.39 |
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