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Extracellular matrix anisotropy is determined by TFAP2C-dependent regulation of cell collisions

The isotropic or anisotropic organisation of biological extracellular matrices has important consequences for tissue function. We study emergent anisotropy using fibroblasts that generate varying degrees of matrix alignment from uniform starting conditions. This reveals that the early migratory path...

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Detalhes bibliográficos
Publicado no:Nat Mater
Main Authors: Park, Danielle, Wershof, Esther, Boeing, Stefan, Labernadie, Anna, Jenkins, Robert P, George, Samantha, Trepat, Xavier, Bates, Paul A, Sahai, Erik
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989216/
https://ncbi.nlm.nih.gov/pubmed/31659294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41563-019-0504-3
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