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Extracellular matrix anisotropy is determined by TFAP2C-dependent regulation of cell collisions

The isotropic or anisotropic organisation of biological extracellular matrices has important consequences for tissue function. We study emergent anisotropy using fibroblasts that generate varying degrees of matrix alignment from uniform starting conditions. This reveals that the early migratory path...

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Bibliografiske detaljer
Udgivet i:Nat Mater
Main Authors: Park, Danielle, Wershof, Esther, Boeing, Stefan, Labernadie, Anna, Jenkins, Robert P, George, Samantha, Trepat, Xavier, Bates, Paul A, Sahai, Erik
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989216/
https://ncbi.nlm.nih.gov/pubmed/31659294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41563-019-0504-3
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