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Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines

To be optimally effective, peptide-based vaccines need to be administered with adjuvants. Many currently available adjuvants are toxic, not biodegradable; they invariably invoke adverse reactions, including allergic responses and excessive inflammation. A nontoxic, biodegradable, biocompatible, self...

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Publicado en:Sci Adv
Main Authors: Skwarczynski, Mariusz, Zhao, Guangzu, Boer, Jennifer C., Ozberk, Victoria, Azuar, Armira, Cruz, Jazmina Gonzalez, Giddam, Ashwini Kumar, Khalil, Zeinab G., Pandey, Manisha, Shibu, Mohini A., Hussein, Waleed M., Nevagi, Reshma J., Batzloff, Michael R., Wells, James W., Capon, Robert J., Plebanski, Magdalena, Good, Michael F., Toth, Istvan
Formato: Artigo
Idioma:Inglês
Publicado: American Association for the Advancement of Science 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989150/
https://ncbi.nlm.nih.gov/pubmed/32064333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax2285
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