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Defects in the exocyst-cilia machinery cause bicuspid aortic valve disease and aortic stenosis

BACKGROUND: Bicuspid aortic valve (BAV) disease is a congenital defect that affects 0.5–1.2% of the population and is associated with co-morbidities including ascending aortic dilation and calcific aortic valve stenosis (CAVS). To date, while a few causal genes have been identified, the genetic basi...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Circulation
المؤلفون الرئيسيون:	Fulmer, Diana, Toomer, Katelynn, Guo, Lilong, Moore, Kelsey, Glover, Janiece, Moore, Reece, Stairley, Rebecca, Lobo, Glenn, Zuo, Xiaofeng, Dang, Yujing, Su, Yanhui, Fogelgren, Ben, Gerard, Patrick, Chung, Dongjun, Heydarpour, Mahyar, Mukherjee, Rupak, Body, Simon C., Norris, Russell A., Lipschutz, Joshua H.
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	2019
الموضوعات:	Article
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6989054/ https://ncbi.nlm.nih.gov/pubmed/31387361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.119.038376
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Defects in the exocyst-cilia machinery cause bicuspid aortic valve disease and aortic stenosis

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