CD82 controls CpG-dependent TLR9 signaling

The tetraspanin CD82 is a potent suppressor of tumor metastasis and regulates several processes including signal transduction, cell adhesion, motility, and aggregation. However, the mechanisms by which CD82 participates in innate immunity are unknown. We report that CD82 is a key regulator of TLR9 t...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Khan, Nida S., Lukason, Daniel P., Feliu, Marianela, Ward, Rebecca A., Lord, Allison K., Reedy, Jennifer L., Ramirez-Ortiz, Zaida G., Tam, Jenny M., Kasperkovitz, Pia V., Negoro, Paige E., Vyas, Tammy D., Xu, Shuying, Brinkmann, Melanie M., Acharaya, Mridu, Artavanis-Tsakonas, Katerina, Frickel, Eva-Maria, Becker, Christine E., Dagher, Zeina, Kim, You-Me, Latz, Eicke, Ploegh, Hidde L., Mansour, Michael K., Miranti, Cindy K., Levitz, Stuart M., Vyas, Jatin M.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988855/
https://ncbi.nlm.nih.gov/pubmed/31408613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901547R
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