Facilitation of MrgprD by TRP-A1 promotes neuropathic pain

Neuropathic pain remains a therapeutic challenge because of its complicated mechanisms. Mas-related GPCR D (MrgprD) is specifically expressed in small-diameter, nociceptive neurons of dorsal root ganglia (DRGs) and is implicated in pain modulation. However, the underlying mechanism of MrgprD involve...

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Veröffentlicht in:FASEB J
Hauptverfasser: Wang, Changming, Gu, Leying, Ruan, Yonglan, Geng, Xiao, Xu, Miao, Yang, Niuniu, Yu, Lei, Jiang, Yucui, Zhu, Chan, Yang, Yan, Zhou, Yuan, Guan, Xiaowei, Luo, Wenqin, Liu, Qin, Dong, Xinzhong, Yu, Guang, Lan, Lei, Tang, Zongxiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988841/
https://ncbi.nlm.nih.gov/pubmed/30148678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800615RR
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