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Stereoselective Four-Component Synthesis of Functionalized 2,3-Dihydro-4-Nitropyrroles

We report a metal-free and stereoselective four-component reaction between α-ketoamides, amines, aromatic aldehydes and β-nitroalkenes or β-pivaloxy-nitroalkanes to obtain 2,3-dihydro-4-nitropyrroles functionalized in every position. The heterocycles accessible using this reaction may have utility i...

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發表在:Front Chem
Main Authors: Wang, Dong, Ma, Xinyue, Dong, Linru, Feng, Hairong, Yu, Peng, Désaubry, Laurent
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988783/
https://ncbi.nlm.nih.gov/pubmed/32039135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2019.00810
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