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Cost-Effectiveness of Risk-Stratified Colorectal Cancer Screening Based on Polygenic Risk: Current Status and Future Potential

BACKGROUND: Although uniform colonoscopy screening reduces colorectal cancer (CRC) mortality, risk-based screening may be more efficient. We investigated whether CRC screening based on polygenic risk is a cost-effective alternative to current uniform screening, and if not, under what conditions it w...

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Dades bibliogràfiques
Publicat a:JNCI Cancer Spectr
Autors principals: Naber, Steffie K, Kundu, Suman, Kuntz, Karen M, Dotson, W David, Williams, Marc S, Zauber, Ann G, Calonge, Ned, Zallen, Doris T, Ganiats, Theodore G, Webber, Elizabeth M, Goddard, Katrina A B, Henrikson, Nora B, van Ballegooijen, Marjolein, Janssens, A Cecile J W, Lansdorp-Vogelaar, Iris
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988584/
https://ncbi.nlm.nih.gov/pubmed/32025627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jncics/pkz086
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