Evasion of autophagy mediated by Rickettsia surface protein OmpB is critical for virulence

Rickettsia are obligate intracellular bacteria that evade antimicrobial autophagy in the host cell cytosol by unknown mechanisms. Other cytosolic pathogens block different steps of autophagy targeting, including the initial step of polyubiquitin coat formation. One mechanism of evasion is to mobiliz...

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Vydáno v:Nat Microbiol
Hlavní autoři: Engström, Patrik, Burke, Thomas P., Mitchell, Gabriel, Ingabire, Nadia, Mark, Kevin G., Golovkine, Guillaume, Iavarone, Anthony T., Rape, Michael, Cox, Jeffery S., Welch, Matthew D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988571/
https://ncbi.nlm.nih.gov/pubmed/31611642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-019-0583-6
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