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Methods for measuring misfolded protein clearance in the budding yeast Saccharomyces cerevisiae

Protein misfolding in the cell is linked to an array of diseases, including cancers, cardiovascular disease, type II diabetes, and numerous neurodegenerative disorders. Therefore, investigating cellular pathways by which misfolded proteins are trafficked and cleared (“protein quality control”) is of...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Samant, Rahul S., Frydman, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988565/
https://ncbi.nlm.nih.gov/pubmed/30910025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.12.039
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