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Methods for measuring misfolded protein clearance in the budding yeast Saccharomyces cerevisiae

Protein misfolding in the cell is linked to an array of diseases, including cancers, cardiovascular disease, type II diabetes, and numerous neurodegenerative disorders. Therefore, investigating cellular pathways by which misfolded proteins are trafficked and cleared (“protein quality control”) is of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Methods Enzymol
Hauptverfasser: Samant, Rahul S., Frydman, Judith
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988565/
https://ncbi.nlm.nih.gov/pubmed/30910025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2018.12.039
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