Vindoline Inhibits RANKL-Induced Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss in Mice

Osteolytic bone diseases, for example postmenopausal osteoporosis, arise from the imbalances between osteoclasts and osteoblasts in the bone remodeling process, whereby osteoclastic bone resorption greatly exceeds osteoblastic bone formation resulting in severe bone loss and deterioration in bone st...

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Vydáno v:Front Pharmacol
Hlavní autoři: Zhan, Yunfei, Liang, Jiamin, Tian, Kun, Che, Zhigang, Wang, Ziyi, Yang, Xue, Su, Yuangang, Lin, Xixi, Song, Fangming, Zhao, Jinmin, Xu, Jiake, Liu, Qian, Zhou, Bo
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987431/
https://ncbi.nlm.nih.gov/pubmed/32038256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01587
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