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Structural Insights Into the Transcriptional Regulation of HigBA Toxin–Antitoxin System by Antitoxin HigA in Pseudomonas aeruginosa

HigB-HigA is a bacterial toxin–antitoxin (TA) system in which the antitoxin HigA can mask the endoribonuclease activity of toxin HigB and repress the transcription of the TA operon by binding to its own promoter region. The opportunistic pathogen Pseudomonas aeruginosa HigBA (PaHigBA) is closely ass...

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Bibliografiske detaljer
Udgivet i:Front Microbiol
Main Authors: Liu, Ying, Gao, Zengqiang, Liu, Guangfeng, Geng, Zhi, Dong, Yuhui, Zhang, Heng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987408/
https://ncbi.nlm.nih.gov/pubmed/32038588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.03158
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