Dynamic changes of Receptor activator of nuclear factor-κB expression in Circulating Tumor Cells during Denosumab predict treatment effectiveness in Metastatic Breast Cancer

Receptor-activator of nuclear-factor –κB-ligand (RANKL) and its receptor RANK have been recently identified as key players in breast cancer bone metastases. Since Circulating Tumor Cells (CTCs) are considered a crucial step of metastatic process, we explored RANK expression on CTCs in metastatic bre...

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Published in:Sci Rep
Main Authors: Pantano, Francesco, Rossi, Elisabetta, Iuliani, Michele, Facchinetti, Antonella, Simonetti, Sonia, Ribelli, Giulia, Zoccoli, Alice, Vincenzi, Bruno, Tonini, Giuseppe, Zamarchi, Rita, Santini, Daniele
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987166/
https://ncbi.nlm.nih.gov/pubmed/31992773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58339-2
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