Zika virus targets the human thymic epithelium

Previous work showed that the thymus can be infected by RNA viruses as HIV and HTLV-1. We thus hypothesized that the thymus might also be infected by the Zika virus (ZIKV). Herein we provide compelling evidence that ZIKV targets human thymic epithelial cells (TEC) in vivo and in vitro. ZIKV-infectio...

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Udgivet i:Sci Rep
Main Authors: Messias, Carolina V., Loss-Morais, Guilherme, Carvalho, Joseane Biso de, González, Mariela N., Cunha, Daniela P., Vasconcelos, Zilton, Arge, Luis W. P., Farias-de-Oliveira, Désio A., Gerber, Alexandra L., Portari, Elyzabeth A., Ferreira, Nilma, Raphael, Lidiane M. S., Bonaldo, Myrna C., Riederer, Ingo, Lopes Moreira, Maria E., Cotta-de-Almeida, Vinicius, Vasconcelos, Ana T. R., Mendes-da-Cruz, Daniella A., Savino, Wilson
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987159/
https://ncbi.nlm.nih.gov/pubmed/31992777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58135-y
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