HSP90A inhibition promotes anti-tumor immunity by reversing multi-modal resistance and stem-like property of immune-refractory tumors

Cancer immunotherapy has emerged as a promising cancer treatment. However, the presence of immune-refractory tumor cells limits its clinical success by blocking amplification of anti-tumor immunity. Previously, we found that immune selection by immunotherapy drives the evolution of tumors toward mul...

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Vydáno v:Nat Commun
Hlavní autoři: Song, Kwon-Ho, Oh, Se Jin, Kim, Suyeon, Cho, Hanbyoul, Lee, Hyo-Jung, Song, Joon Seon, Chung, Joon-Yong, Cho, Eunho, Lee, Jaeyoon, Jeon, Seunghyun, Yee, Cassian, Lee, Kyung-Mi, Hewitt, Stephen M., Kim, Jae-Hoon, Woo, Seon Rang, Kim, Tae Woo
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987099/
https://ncbi.nlm.nih.gov/pubmed/31992715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14259-y
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