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Genome-Wide CRISPR Screen Identifies Host Factors Required by Toxoplasma gondii Infection

Toxoplasma gondii are obligate intracellular protoza, and due to their small genome and limited encoded proteins, they have to exploit host factors for entry, replication, and dissemination. Such host factors can be defined as host dependency factors (HDFs). Though HDFs are inessential for cell viab...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Infect Microbiol
Hauptverfasser: Wu, Shui-Zhen, Wei, Hai-Xia, Jiang, Dan, Li, Sheng-Min, Zou, Wei-Hao, Peng, Hong-Juan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987080/
https://ncbi.nlm.nih.gov/pubmed/32039045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00460
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