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A causal mechanism for childhood acute lymphoblastic leukaemia
In this Review, I present evidence supporting a multi-factorial causation of childhood acute lymphoblastic leukaemia (ALL), a major subtype of paediatric cancer. ALL evolves in two discrete steps. First, in utero initiation by fusion gene formation or hyperdiploidy generates a covert, pre-leukaemic...
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| Udgivet i: | Nat Rev Cancer |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6986894/ https://ncbi.nlm.nih.gov/pubmed/29784935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41568-018-0015-6 |
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