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Multiplex CRISPR/Cas screen in regenerating haploid limbs of chimeric Axolotls

Axolotls and other salamanders can regenerate entire limbs after amputation as adults, and much recent effort has sought to identify the molecular programs controlling this process. While targeted mutagenesis approaches like CRISPR/Cas9 now permit gene-level investigation of these mechanisms, geneti...

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Publicat a:eLife
Autors principals: Sanor, Lucas D, Flowers, Grant Parker, Crews, Craig M
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986871/
https://ncbi.nlm.nih.gov/pubmed/31989926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48511
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