Prevalence and association of pks(+) Escherichia coli with colorectal cancer in patients at the University Malaya Medical Centre, Malaysia

Escherichia coli (E. coli) from the B2 phylogenetic group is implicated in colorectal cancer (CRC) as it possesses a genomic island, termed polyketide synthetase (pks), which codes for the synthesis of colibactin, a genotoxin that induces DNA damage, cell cycle arrest, mutations and chromosomal inst...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Iyadorai, Thevambiga, Mariappan, Vanitha, Vellasamy, Kumutha Malar, Wanyiri, Jane Wangui, Roslani, April Camilla, Lee, Goh Khean, Sears, Cynthia, Vadivelu, Jamuna
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986756/
https://ncbi.nlm.nih.gov/pubmed/31990962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228217
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