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Prevalence and association of pks(+) Escherichia coli with colorectal cancer in patients at the University Malaya Medical Centre, Malaysia

Escherichia coli (E. coli) from the B2 phylogenetic group is implicated in colorectal cancer (CRC) as it possesses a genomic island, termed polyketide synthetase (pks), which codes for the synthesis of colibactin, a genotoxin that induces DNA damage, cell cycle arrest, mutations and chromosomal inst...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Iyadorai, Thevambiga, Mariappan, Vanitha, Vellasamy, Kumutha Malar, Wanyiri, Jane Wangui, Roslani, April Camilla, Lee, Goh Khean, Sears, Cynthia, Vadivelu, Jamuna
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986756/
https://ncbi.nlm.nih.gov/pubmed/31990962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228217
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