Cosmc Disruption-Mediated Aberrant O-glycosylation Suppresses Breast Cancer Cell Growth via Impairment of CD44

BACKGROUND: Breast cancer remains the most lethal malignancy in women worldwide. Aberrant O-glycosylation is closely related to many human diseases, including breast carcinoma; however, its precise role in cancer development is insufficiently understood. Cosmc is an endoplasmic reticulum-localized c...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Manag Res
Main Authors: Du, Tan, Jia, Xingyuan, Dong, Xichen, Ru, Xiaoli, Li, Lina, Wang, Yakun, Liu, Jian, Feng, Guosheng, Wen, Tao
Format: Artigo
Jezik:Inglês
Izdano: Dove 2020
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986418/
https://ncbi.nlm.nih.gov/pubmed/32158257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S234735
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