Pharmacokinetics and Pharmacodynamics of Anti-infective Agents during Continuous Veno-venous Hemofiltration in Critically Ill Patients: Lessons Learned from an Ancillary Study of the IVOIRE Trial

BACKGROUND: Hemofiltration rate, changes in blood and ultrafiltration flow, and discrepancies between the prescribed and administered doses strongly influence pharmacokinetics (PK) and pharmacodynamics (PD) of antimicrobial agents during continuous veno-venous hemofiltration (CVVH) in critically ill...

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Veröffentlicht in:J Transl Int Med
Hauptverfasser: Breilh, Dominique, Honore, Patrick M., De Bels, David, Roberts, Jason A., Gordien, Jean Baptiste, Fleureau, Catherine, Dewitte, Antoine, Coquin, Julien, Rozé, Hadrien, Perez, Paul, Attou, Rachid, Redant, Sebastien, Kugener, Luc, Saux, Marie-Claude, Spapen, Herbert D., Ouattara, Alexandre, Joannes-Boyau, Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: Sciendo 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985915/
https://ncbi.nlm.nih.gov/pubmed/32010602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2478/jtim-2019-0031
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