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Role of TRP channels in G(q)-coupled protease-activated receptor 1-mediated activation of mouse nodose pulmonary C-fibers
We evaluated the mechanisms underlying protease-activated receptor 1 (PAR1)-mediated activation of nodose C-fibers in mouse lungs. The PAR1-induced action potential discharge at the terminals was strongly inhibited in phospholipase C-β3 (PLCβ3)-deficient animals. At the level of the cell soma, PAR1...
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| Izdano u: | Am J Physiol Lung Cell Mol Physiol |
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| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6985869/ https://ncbi.nlm.nih.gov/pubmed/31664854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00301.2019 |
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