Prenatal metyrapone treatment modulates neonatal cerebrovascular structure, function, and vulnerability to mild hypoxic-ischemic injury

This study explored the hypothesis that late gestational reduction of corticosteroids transforms the cerebrovasculature and modulates postnatal vulnerability to mild hypoxic-ischemic (HI) injury. Four groups of Sprague-Dawley neonates were studied: 1) Sham-Control, 2) Sham-MET, 3) HI-Control, and 4)...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Franco, P. Naomi, Durrant, Lara M., Carreon, Desirelys, Haddad, Elizabeth, Vergara, Adam, Cascavita, Catherine, Obenaus, Andre, Pearce, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985796/
https://ncbi.nlm.nih.gov/pubmed/31577477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00145.2019
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