Activity of Imipenem-Relebactam against a Large Collection of Pseudomonas aeruginosa Clinical Isolates and Isogenic β-Lactam-Resistant Mutants

Imipenem and imipenem-relebactam MICs were determined for 1,445 Pseudomonas aeruginosa clinical isolates and a large panel of isogenic mutants showing the most relevant mutation-driven β-lactam resistance mechanisms. Imipenem-relebactam showed the highest susceptibility rate (97.3%), followed by col...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Fraile-Ribot, Pablo A., Zamorano, Laura, Orellana, Rocío, del Barrio-Tofiño, Ester, Sánchez-Diener, Irina, Cortes-Lara, Sara, López-Causapé, Carla, Cabot, Gabriel, Bou, Germán, Martínez-Martínez, Luis, Oliver, Antonio
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2020
Ämnen:
Mechanisms of Resistance
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985745/
https://ncbi.nlm.nih.gov/pubmed/31740559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02165-19
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