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Antimicrobial Therapy in the Context of the Damage-Response Framework: the Prospect of Optimizing Therapy by Reducing Host Damage

By design, antimicrobial agents act directly on microbial targets. These drugs aim to eliminate microbes and are remarkably effective against susceptible organisms. Nonetheless, some patients succumb to infectious diseases despite appropriate antimicrobial therapy. Today, with very few exceptions, p...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Pirofski, Liise-anne, Casadevall, Arturo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985739/
https://ncbi.nlm.nih.gov/pubmed/31740558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01800-19
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