Biofilms of Mycobacterium abscessus Complex Can Be Sensitized to Antibiotics by Disaggregation and Oxygenation

Pulmonary infection with the multidrug-resistant Mycobacterium abscessus complex (MABSC) is difficult to treat in individuals with cystic fibrosis (CF). MABSC grows as biofilm aggregates in CF patient lungs, which are known to have anaerobic niches. How aggregation and anoxic conditions affect antib...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Kolpen, Mette, Jensen, Peter Østrup, Qvist, Tavs, Kragh, Kasper Nørskov, Ravnholt, Cecillie, Fritz, Blaine Gabriel, Johansen, Ulla Rydahl, Bjarnsholt, Thomas, Høiby, Niels
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2020
Onderwerpen:
Mechanisms of Resistance
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985723/
https://ncbi.nlm.nih.gov/pubmed/31740557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01212-19
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