Biofilms of Mycobacterium abscessus Complex Can Be Sensitized to Antibiotics by Disaggregation and Oxygenation

Pulmonary infection with the multidrug-resistant Mycobacterium abscessus complex (MABSC) is difficult to treat in individuals with cystic fibrosis (CF). MABSC grows as biofilm aggregates in CF patient lungs, which are known to have anaerobic niches. How aggregation and anoxic conditions affect antib...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Kolpen, Mette, Jensen, Peter Østrup, Qvist, Tavs, Kragh, Kasper Nørskov, Ravnholt, Cecillie, Fritz, Blaine Gabriel, Johansen, Ulla Rydahl, Bjarnsholt, Thomas, Høiby, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985723/
https://ncbi.nlm.nih.gov/pubmed/31740557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01212-19
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