Inhibition of Ctsk modulates periodontitis with arthritis via downregulation of TLR9 and autophagy

OBJECTIVES: The mechanisms underlying the effects of Toll‐like receptor 9 (TLR9) and autophagy on rheumatoid arthritis (RA)‐aggravated periodontitis are unclear. We aimed to explore a novel target, cathepsin K (Ctsk)‐mediated TLR9‐related autophagy, during the progress of periodontitis with RA. MATE...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Wei, Wei, Ren, Jie, Yin, Wuwei, Ding, Handong, Lu, Qiuyu, Tan, Liangyu, Deng, Shibing, Liu, Jie, Yang, Qin, Wang, Jiajia, Wang, Min, Yue, Yuan, Hao, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985664/
https://ncbi.nlm.nih.gov/pubmed/31737959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12722
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