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TIM‐4 interference in Kupffer cells against CCL4‐induced liver fibrosis by mediating Akt1/Mitophagy signalling pathway

OBJECTIVES: T‐cell immunoglobulin domain and mucin domain‐4 (TIM‐4) is selectively expressed on antigen‐presenting cells (APCs) and modulates various immune responses. However, the role of TIM‐4 expressed by Kupffer cells (KCs) in liver fibrosis remains unclear. The present study aimed to explore wh...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Prolif
Hauptverfasser: Wu, Hao, Chen, Guoyong, Wang, Jingyuan, Deng, Minghua, Yuan, Fangchao, Gong, Jianping
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985653/
https://ncbi.nlm.nih.gov/pubmed/31755616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12731
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