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IRF-5 Expression in Myeloid Cells Is Required for Splenomegaly in L. donovani Infected Mice

Persistent Leishmania donovani infection is characterized by chronic inflammation, immune suppression, and splenomegaly. We have previously reported that the transcription factor interferon regulatory factor 5 (IRF-5) is largely responsible for inducing the inflammatory response and maintaining prot...

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Podrobná bibliografie
Vydáno v:Front Immunol
Hlavní autoři: Mai, Linh Thuy, Smans, Mélina, Silva-Barrios, Sasha, Fabié, Aymeric, Stäger, Simona
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985270/
https://ncbi.nlm.nih.gov/pubmed/32038622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03071
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