Resting-state connectivity stratifies premanifest Huntington’s disease by longitudinal cognitive decline rate

Patient stratification is critical for the sensitivity of clinical trials at early stages of neurodegenerative disorders. In Huntington’s disease (HD), genetic tests make cognitive, motor and brain imaging measurements possible before symptom manifestation (pre-HD). We evaluated pre-HD stratificatio...

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Vydáno v:Sci Rep
Hlavní autoři: Polosecki, Pablo, Castro, Eduardo, Rish, Irina, Pustina, Dorian, Warner, John H., Wood, Andrew, Sampaio, Cristina, Cecchi, Guillermo A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985137/
https://ncbi.nlm.nih.gov/pubmed/31988371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58074-8
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