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Negative impact of malignant effusion on osimertinib treatment for non-small cell lung cancer harboring EGFR mutation

3rd-generation epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs), including osimertinib, have reasonable efficacy in non–small-cell lung cancers (NSCLC) with EGFR mutations. However, the efficacy of osimertinib in NSCLC patients with fluids, such as pleural, pericardial and abd...

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Détails bibliographiques
Publié dans:Invest New Drugs
Auteurs principaux: Kawamura, Takahisa, Kenmotsu, Hirotsugu, Kobayashi, Haruki, Omori, Shota, Nakashima, Kazuhisa, Wakuda, Kazushige, Ono, Akira, Naito, Tateaki, Murakami, Haruyasu, Mori, Keita, Endo, Masahiro, Takahashi, Toshiaki
Format: Artigo
Langue:Inglês
Publié: Springer US 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985082/
https://ncbi.nlm.nih.gov/pubmed/31183631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-019-00808-1
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