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Intranasal Neuropeptide Y Blunts Lipopolysaccharide-Evoked Sickness Behavior but Not the Immune Response in Mice

Neuropeptide Y (NPY) has been demonstrated to exert stress buffering effects and promote resilience. Non-invasive intranasal (IN) application of NPY to rodents is able to mitigate traumatic stress-induced behavioral changes as well as dysfunction of the hypothalamic-pituitary-adrenal (HPA) axis. How...

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Опубликовано в: :Neurotherapeutics
Главные авторы: Zenz, Geraldine, Farzi, Aitak, Fröhlich, Esther E., Reichmann, Florian, Holzer, Peter
Формат: Artigo
Язык:Inglês
Опубликовано: Springer International Publishing 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985076/
https://ncbi.nlm.nih.gov/pubmed/31338703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-019-00758-9
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