Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination

Oligodendrocytes (OLs) myelinate axons and provide electrical insulation and trophic support for neurons in the central nervous system (CNS). Platelet-derived growth factor (PDGF) is critical for steady-state number and differentiation of oligodendrocyte precursor cells (OPCs), but its downstream ta...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Zhou, Liang, Shao, Chong-Yu, Xie, Ya-Jun, Wang, Na, Xu, Si-Min, Luo, Ben-Yan, Wu, Zhi-Ying, Ke, Yue Hai, Qiu, Mengsheng, Shen, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984811/
https://ncbi.nlm.nih.gov/pubmed/31944179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52056
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