Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination

Oligodendrocytes (OLs) myelinate axons and provide electrical insulation and trophic support for neurons in the central nervous system (CNS). Platelet-derived growth factor (PDGF) is critical for steady-state number and differentiation of oligodendrocyte precursor cells (OPCs), but its downstream ta...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Zhou, Liang, Shao, Chong-Yu, Xie, Ya-Jun, Wang, Na, Xu, Si-Min, Luo, Ben-Yan, Wu, Zhi-Ying, Ke, Yue Hai, Qiu, Mengsheng, Shen, Ying
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2020
Pynciau:
Neuroscience
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984811/
https://ncbi.nlm.nih.gov/pubmed/31944179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.52056
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