MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint

A switch from autophagy to apoptosis is implicated in chondrocytes during the osteoarthritis (OA) progression with currently unknown mechanism(s). In this study we utilized a flow fluid shear stress (FFSS) model in cultured chondrocytes and a unilateral anterior crossbite (UAC) animal model. We foun...

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Dettagli Bibliografici
Pubblicato in:Autophagy
Autori principali: Yang, Hongxu, Wen, Yi, Zhang, Mian, Liu, Qian, Zhang, Hongyun, Zhang, Jing, Lu, Lei, Ye, Tao, Bai, Xiaochun, Xiao, Guozhi, Wang, Meiqing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2019
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984599/
https://ncbi.nlm.nih.gov/pubmed/31007149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1606647
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